Video overview:
- Novelty and Inventive Step
- Prior art must necessarily lead to the claimed polymorph to be novelty destroying
- Watch out for inherent disclosures in prior art—methods may implicitly produce polymorphs even if structural data isn't provided.
- Provide experimental evidence if needed to show prior art does not produce the claimed polymorph.
- Emphasise any advantages or unexpected properties of the polymorph, supported by data, to support an inventive step
- Clarity
- Provide a clear, precise definition of the polymorph.
- Clearly define the crystalline form using appropriate physicochemical parameters and measurement conditions.
- Sufficiency
- Clearly describe how to prepare the polymorph. If preparation requires seeding crystals, disclose how to prepare the seed in the application
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