Fabian M. Koenigbauer and Annette K. Kwok published "Incentives to Repurpose Existing Drugs for Orphan Indications" in ACS Medicinal Chemistry Letters (DOI: 10.1021/acsmedchemlett.5b00276) on July 23, 2015. This article discusses the Orphan Drug Act and its success in providing incentives to find cures for orphan diseases, as well as the 21st Century Cures Act and the Orphan Product Extension Now Accelerating Cures and Treatment Act of 2015, pending bills created to provide additional incentives to innovators to repurpose existing drugs for the treatment of orphan diseases.
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